Immunology MCQ
Limiting factors can affect _________________ (select all that apply):
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All of these
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Life on the earth depends on interaction of gravity, the cycling of matter, and the ____.
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One-way flow of energy
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Lettuce seeds exposed to far-red light, blue light, and then red light ______.
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R →FR→R→FR→R
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L-dopa is used to treat _____
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Parkinson's disease
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The person credited with the axiom, every cell from a cell is __________.
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Rudolf Virchow
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The correct composition of the membrane attack complex is given by_______________
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Innate immunity and adaptive immunity are both _____.
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Characteristics of all vertebrate animals
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A circulating white blood cell that is a factor in inflammation is a(n) ________ .
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Beta cell destruction that causes type 1 diabetes mellitus is a(n) __________.
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Type IV (delayed) hypersensitivity
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An antigen must be at least ________ amino acids long to be effective in a vaccine.
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All of the following processes can be activated by complement except __________.
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Antibody production
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Activation of c3 results in __________.
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All of the listed choices
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Tc cells express a(n) ________ protein co-receptor.
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Natural killer (nk) cells __________.
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Can kill cancer cells before the immune system is activated.
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Four cardinal signs of ____________ are recognized.
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Inflammation
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Tissue rejection after an organ transplant is least likely due to the action of _________.
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Regulatory T cells
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The serum used for emergency treatment of snakebites stimulates __________ immunity.
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Artificial passive
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T-independent humoral immunity may be stunted in children because __________.
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The repertoire of B cells in children is not fully developed
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A change in the immune system that rarely accompanies aging is __________.
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Improved immunological surveillance
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One group of proteolytic enzymes secreted by natural killer (nk) cells is __________.
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Granzymes
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Bronchoconstriction, dyspnea, and widespread vasodilation are all characteristics of __________.
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Anaphylactic shock
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A secondary response to an infectious agent has a _______ latent phase than a primary response has.
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The "immuno" part of elisa refers to a critical component of the assay, the _____.
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Antibodies
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During the inflammatory response ______ degranulate and release ________.
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Mast cells; histamine
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The cell that dominates the deep cortical region of a lymph node is the ________ cell.
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Antibiotics administered in human medicine work against bacterial infections by __________.
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Interfering with an aspect of bacterial metabolism or structure that differs from that of eukaryotic cells
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Treatment of an abscess often requires that it be surgically drained because ______.
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The wall of the abscess prevents neutrophils from entering the pus and attacking the pathogens
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The redness and heat of an inflamed area are due to a local hyperemia caused by ________.
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Vasodilation
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Phagocyte mobilization involves ________.
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Cytotoxic
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Antigen presentation is __________.
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Presented by specialized peptide display molecules on host cell.
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An advantage to adaptive immunity is ________.
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Its memory cells that provide quicker, larger and more efficient immune response upon second exposure to an antigen
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An advantage of innate immunity is ________.
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Its barriers that prevent pathogens from entering into the body.
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Allergic reactions to penicillins are considered a(n) _____ hypersensitivity.
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Immediate
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Allergens differ from antigens because ________.
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Allergens produce an abnormally large immune response to what is an otherwise harmless particle
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A vaccine is effective because ________.
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The secondary response of the adaptive immunity is faster and more efficient than the primary response.
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T-independent humoral immunity __________.
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The repertoire of B cells in children is not fully developed
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T cells achieve self tolerance in the __________
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Il 2 is involved in __________ tc cells
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Self-stimulation of clonal
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T cells _____ pathogens.
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Defense against
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Dividing lymphocytes can be found in the ________ of the lymphatic nodule.
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Germinal center
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The immune system normally discriminates between __________ antigens.
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Self and nonself
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Type a blood can safely donate rbcs to _____________ and can receive rbcs of type ___________.
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A fruit fly, internally infected by a potentially pathogenic fungus, is protected by its _____.
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Antimicrobial peptides
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The lymphocytes that enter tissues and directly attack antigens are __________ cells.
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Cytotoxic T
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The birth of t cells takes place in the ____________ bone marrow.
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Most antibodies and ____ _____ respond to the site of ______ _______ on a foreign molecule.
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T cells, highest antigenicity
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Innate immunity _____.
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Is activated immediately upon infection
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Helper t cells are part of _____.
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Helper T cells are part of cell-mediated immune responses. Cell-mediated immunity depends on the activation of T lymphocytes.
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Vertebrate immune cells, which are phagocytic, include ________.
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All of the above
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Class i mhc molecules __________.
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Activate cytotoxic T cells
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Class i major histocompatibility complex molecules are found on ____________ cells.
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All nucleated
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Yearly vaccination of humans for influenza viruses is necessary because _____.
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Rapid mutation in flu viruses alters the surface proteins in infected host cells
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Without the positive selection process in lymphocyte maturation ________.
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T-cells would not be able to properly bind to APC's and therefore not be activated by them
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The process of diapedesis is important because __________.
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It allows white blood cells to leave the vessel system and attack pathogens in the tissues
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The secondary response in humoral immunity occurs when memory cells bind to ______.
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The helper t-cell clones stimulate antibody production by _____.
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Plasma cells
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The eyes and the respiratory tract are both protected against infections by _____.
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The secretion of lysozyme onto their surface
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T lymphocytes are to the _____ as b lymphocytes are to the _____.
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Thymus; bone marrow
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Prostaglandins function to _________ during an immune response.
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Induce fever by raising the body's temperature
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Plasma cells ________.
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Have a great deal of rough endoplasmic reticulum reflecting the fact that they secrete a tremendous amount of protein (antibody
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Monoclonal antibodies are used for the diagnosis of all of the following except ________.
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Juvenile diabetes
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Innate immunity and acquired immunity are both _____.
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Characteristics of all vertebrate animals
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In an antibody molecule, the __________ region mediates binding to host cells.
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Il 2 is involved in __________ tc cells
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Self-stimulation of
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Igm is the first class of antibodies to be made during an immune response because ____.
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The gene for the mu Fc region is the first to be attached to the variable region gene
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Helper t-lymphocytes secrete ________ to stimulate the proliferation of b-lymphocytes.
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Cytokines
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Fever is induced at the systemic level by ________, which is an endogenous pyrogen.
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Cytotoxic t (tc) cells are like natural killer (nk) cells because they both __________.
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Secrete granzymes and perforin
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Cd8 markers are to ________ t cells as cd4 markers are to ________ t cells.
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Cytoxic; helper
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Autoimmune diseases are an example of a(n) ________ response by the immune system.
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Incorrect
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Antibodies are __________ produced in response to an antigen.
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________ is the capacity to mount a secondary response to the same antigen.
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________ exists when the immune system does not respond to a particular antigen.
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Tolerance
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Antimicrobial peptides called ________ are secreted in sweat and damage bacteria and fungi.
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Dermcidins
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Antigens that depend on the function of t-helper cells are called __________ antigens.
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T-dependent
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Antigens bound to mhc ii activate __________.
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Helper T cells
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Any substance that triggers an immune response in the body is called a(n) ________.
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A characteristic symptom of necrotizing fasciitis is that the pain __________.
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Is disproportionate to the appearance of the infection
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Antibodies are produced and secreted by ______
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Plasma cells
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A primary immune response is the ______.
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Immune response elicited by the first exposure of lymphocytes to a particular antigen
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When an antigen is bound to a class ii mhc protein, it can activate a ________ cell.
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When an antigen is bound to a class i mhc molecule, it can stimulate a ________ cell.
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Cytotoxic T
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White blood cells and ____ carry out innate immune responses
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Defensive proteins
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This medullary region of the lymph node contains primarily ________.
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Macrophages
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Naturally acquired passive immunity can result from the _____.
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Placental transfer of antibodies
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B cells respond to the initial antigen challenge by ________
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Producing progeny cells that include plasma cells and memory cells
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Antibody functions include all of the following except ________.
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Cross-linking cell-bound antigens on red blood cells when blood types are properly matched
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When antibodies bind antigens, the clumping of antigens results from _____.
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The antibody having at least two binding regions
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This variable region gives an antibody ______ for an _______.
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Specificity, antigen
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Memory t cells can be up to __________ old.
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T cells of the immune system include _____.
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Cytotoxic and helper cells
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Proteins on the surface of phagocytes called ________ aid in the detection of pathogen molecules.
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Most often, antigens are composed of __________.
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Glycoproteins
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Membrane attack complex (mac) kills by ________.
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Disrupting the selectively permeability of a bacteria's plasma membrane
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Immunological memory accounts for _____.
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The ancient observation that someone who had recovered from the plague could safely care for those newly diseased.
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Histamine is released from the _____ cells
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Mast cells
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Exogenous antigens are processed for immune recognition by ________ cells.
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Dendritic and macrophage
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Complement fixation cannot lead to __________.
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Endogenous pyrexia
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Clonal selection of b cells ________.
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Results in the formation of plasma cells
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Cell-mediated immunity is to t cells as antibody-mediated immunity is to ___________.
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Antibody structures are perfectly suited to directly link ______ to ______.
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Antigen, immune cell
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Antibodies are ___ proteins while antigens are ___ proteins.
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Self-produced; foreign
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Activated cd8 t cells become __________.
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Cytotoxic T cells
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__________ is not a cardinal sign characteristic of inflammation.
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Impaired use
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